Question No 4:
A 55 year old patient with Stage 2A HER2 positive breast cancer receiving every three week adjuvant trastuzumab therapy. At her appointment, she complains of fatigue and the inability to do her normal daily activities. Her lab results show that she is anemic with a hemoglobin of 9.9 g/dL (hematocrit 29%). Which of the following treatments would be best for this patient?
A. Start epoetin alfa 40,000 units SQ weekly
B. Begin darbepoetin alfa 500 mcg SQ every three weeks
C. Initiate iron sucrose 200 mg IV followed by darbepoetin 500 mcg SQ every 3 weeks
D. No erythropoiesis stimulating agent (ESA) is indicated
Answer: D
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